Blar i forfatter "Haldorsen, Bjørg"
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Antimicrobial susceptibility profiles of clinically important bacterial pathogens at the Kamuzu Central Hospital in Lilongwe, Malawi
Choonara, Faheema E.; Haldorsen, Bjørg; Ndhlovu, Isaac; Saulosi, Osborne; Maida, Tarsizio; Lampiao, Fanuel; Simonsen, Gunnar Skov; Essack, Sabiha Y.; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-04-01)Background The aim of this prospective study was to ascertain antimicrobial resistance (AMR) in clinical bacterial pathogens from in-hospital adult patients at a tertiary hospital in Lilongwe, Malawi. Methods<p> <p>Clinical specimens (blood culture, pus, urine and cerebrospinal fluid) collected during June to December 2017 were examined for bacterial growth in standard aerobic conditions. One ... -
Emergence and dissemination of antimicrobial resistance in Escherichia coli causing bloodstream infections in Norway in 2002–17: a nationwide, longitudinal, microbial population genomic study
Gladstone, Rebecca Ashley; McNally, Alan; Pöntinen, Anna Kaarina; Tonkin-Hill, Gerry; Lees, John A.; Skytén, Kusti Onni; Cléon, Francois Pierre Alexandre; Christensen, Martin Owczarek Korsner; Haldorsen, Bjørg; Bye, Kristina K.; Gammelsrud, Karianne Wiger; Hjetland, Reidar; Kümmel, Angela; Larsen, Hege; Lindemann, Paul Christoffer; Löhr, Iren Høyland; Marvik, Åshild; Nilsen, Einar; Noer, Marie Therese; Simonsen, Gunnar Skov; Steinbakk, Martin; Tofteland, Ståle; Vattøy, Marit; Bentley, Stephen D.; Croucher, Nicholas J.; Parkhill, Julian; Johnsen, Pål Jarle; Samuelsen, Ørjan; Corander, Jukka (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-05-10)Background - The clonal diversity underpinning trends in multidrug resistant Escherichia coli causing bloodstream infections remains uncertain. We aimed to determine the contribution of individual clones to resistance over time, using large-scale genomics-based molecular epidemiology.<p> <p>Methods - This was a longitudinal, E coli population, genomic, cohort study that sampled isolates from ... -
Epidemiological and molecular characterization of Streptococcus pneumoniae carriage strains in pre-school children in Arkhangelsk, northern European Russia, prior to the introduction of conjugate pneumococcal vaccines
Jensen, V. Vorobieva S.; Furberg, Anne-Sofie; Slotved, Hans-Christian; Bazhukova, Tatiana; Haldorsen, Bjørg; Caugant, Dominique A.; Sundsfjord, Arnfinn; Valentiner-Branth, Palle; Simonsen, Gunnar Skov (Journal article; Tidsskriftartikkel; Peer reviewed, 2020-04-15)<p><i>Background - </i>The 13-valent Pneumococcal Conjugate Vaccine (PCV-13) was introduced in the National Immunization Programme (NIP) schedule in Russia in March 2014. Previously, the 7-valent Pneumococcal Conjugate Vaccine (PCV-7) was marketed in Russia in 2009 but has never been offered for mass vaccination. A carriage study was performed among children in Arkhangelsk in 2006. The objective was ... -
High prevalence of multidrug resistant ESBL- and plasmid mediated AmpC-producing clinical isolates of Escherichia coli at Maputo Central Hospital, Mozambique
Estaleva, Calvina E.L.; Zimba, Tomas F.; Sekyere, John Osei; Govinden, Usha; Chenia, Hafizah Y.; Simonsen, Gunnar S.; Haldorsen, Bjørg; Essack, Sabiha Y.; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2021-01-06)Background: Epidemiological data of cephalosporin-resistant Enterobacterales in Sub-Saharan Africa is still restricted,and in particular in Mozambique. The aim of this study was to detect and characterize extended-spectrum β-lactamase (ESBL) - and plasmid-mediated AmpC (pAmpC)-producing clinical strains of Escherichia coli at Maputo Central Hospital (MCH), a 1000-bed reference hospital in Maputo, ... -
Identification of VIM-2-producing Pseudomonas aeruginosa from Tanzania is associated with sequence types 244 and 640 and the location of blaVIM-2 in a TniC integron
Moyo, Sabrina John; Haldorsen, Bjørg; Aboud, Said; Blomberg, Bjørn; Maselle, Samuel Y; Sundsfjord, Arnfinn; Langeland, Nina; Samuelsen, Ørjan (Journal article; Tidsskriftartikkel; Peer reviewed, 2014) -
Molecular and epidemiological characterization of carbapenemase-producing Enterobacteriaceae in Norway, 2007 to 2014
Samuelsen, Ørjan; Overballe-Petersen, Søren; Bjørnholt, Jørgen; Brisse, Sylvain; Doumith, Michel; Woodford, Neil; Hopkins, Katie L.; Aasnæs, Bettina; Haldorsen, Bjørg; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2017-11-15)The prevalence of carbapenemase-producing Enterobacteriaceae (CPE) is increasing worldwide. Here we present associated patient data and molecular, epidemiological and phenotypic characteristics of all CPE isolates in Norway from 2007 to 2014 confirmed at the Norwegian National Advisory Unit on Detection of Antimicrobial Resistance. All confirmed CPE isolates were characterized pheno- and genotypically, ... -
Molecular Epidemiological Characterisation of ESBL- and Plasmid-Mediated AmpC-Producing Escherichia coli and Klebsiella pneumoniae at Kamuzu Central Hospital, Lilongwe, Malawi
Choonara, Faheema Ebrahim; Haldorsen, Bjørg; Janice, Jessin; Mbanga, Joshua; Ndhlovu, Isaac; Saulosi, Osborne; Maida, Tarsizio; Lampiao, Fanuel; Simonsen, Gunnar Skov; Essack, Sabiha Yusuf; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2022-09-14)The global rise in infections caused by multidrug resistant (MDR) Enterobacterales poses a public health problem. We have performed a molecular epidemiological characterisation of representative plasmid-mediated AmpC (pAmpC) and ESBL-positive clinical isolates of Escherichia coli (n = 38) and Klebsiella pneumoniae (n = 17) from a tertiary hospital in Malawi collected in 2017. BlaCTX-M-15 was the ... -
Nationwide, population-based observational study of the molecular epidemiology and temporal trend of carbapenemase-producing Enterobacterales in Norway, 2015 to 2021
Ljungquist, Oskar; Haldorsen, Bjørg; Pöntinen, Anna Kaarina; Janice, Jessin; Josefsen, Ellen Haldis; Elstrøm, Petter; Kacelnik, Oliver; Sundsfjord, Arnfinn; Samuelsen, Ørjan; Handal, Nina; Ranheim, Trond Egil; Hansen, Bent-Are; Mjøen, Andreas Fossum; Lindemann, Paul Christoffer; Nilsen, Einar; Zaragkoulias, Kyriakos; Larsen, Hege Elisabeth; Bjørnholt, Jørgen; Gammelsrud, Karianne Wiger; Jakovljev, Aleksandra; Löhr, Iren Høyland; Bredberg, Anders; Marvik, Åshild; Minge, Christina; Tofteland, Ståle; Papp, Kristina; Onken, Annette; Weme, Einar Tollaksen; Guennigsman, Brian Albert (Journal article; Tidsskriftartikkel; Peer reviewed, 2023-07-06)National and regional carbapenemaseproducing Enterobacterales (CPE) surveillance is essential to understand the burden of antimicrobial resistance, elucidate outbreaks, and develop infection-control or antimicrobial-treatment recommendations. Aim: This study aimed to describe CPE and their epidemiology in Norway from 2015 to 2021. Methods: A nationwide, population-based observational study of ... -
Performance of the EUCAST disc diffusion method and two MIC methods in detection of Enterobacteriaceae with reduced susceptibility to meropenem: the NordicAST CPE study.
Haldorsen, Bjørg; Giske, Christian G; Hansen, Dennis S; Helgason, Kristjan Orri; Kahlmeter, Gunnar; Löhr, Iren Høyland; Matuschek, Erika; Österblad, Monica; Rantakokko-Jalava, Kaisu; Wang, Mikala; Småbrekke, Lars; Samuelsen, Ørjan; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-07-24)Objectives: To examine performance of EUCAST disc diffusion and supplementary MIC methods for detection of Enterobacteriaceae with reduced susceptibility to meropenem using EUCAST screening recommendations.<p> <p>Methods: Sixty-one Nordic laboratories delivered data on EUCAST disc diffusion (n " 61), semi-automated meropenem MIC (n " 23; VITEK2, n " 20 and Phoenix, n " 3) and gradient meropenem ... -
Performance of the EUCAST disk diffusion method, the CLSI agar screen method, and the Vitek 2 automated antimicrobial susceptibility testing system for detection of clinical isolates of enterococci with low- and medium-level VanB-type vancomycin resistance: A multicenter study
Hegstad, Kristin; Giske, Christian G.; Haldorsen, Bjørg; Matuschek, Erika; Schønning, Kristian; Leegaard, Truls Michael; Kahlmeter, Gunnar; Sundsfjord, Arnfinn (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)